Blar i forfatter "Kubiak, Julia Magdalena"
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Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency
Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Joakimsen, Ragnar Martin; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-04-05)In observational studies, vitamin D deficiency is a risk factor for low bone density and future fractures, whereas a causal relation has been difficult to show in randomized controlled trials (RCTs). Similarly, vitamin D deficiency has been associated with increased bone turnover, but RCTs with vitamin D have not shown conclusive effects. This could be due to inclusion of vitamin D sufficient subjects ... -
Four months vitamin D supplementation to vitamin D insufficient individuals does not improve muscular strength: A randomized controlled trial
Grimnes, Guri; Kubiak, Julia Magdalena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-16)<i>Main objective</i> - The inconsistent results on the effects of vitamin D on muscle strength reported by intervention trials may partly be explained by inclusion of vitamin D sufficient individuals. The main objective was to study whether vitamin D supplementation will improve muscle strength in men and women with low serum vitamin D status, as measured by 25-hydroxyvitamin D (25(OH)D) at ... -
No improvement in depressive symptoms by vitamin D supplementation: results from a randomised controlled trial
Jorde, Rolf; Kubiak, Julia Magdalena (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-22)In observational studies, vitamin D deficiency is associated with depressive symptoms. However, randomised controlled trials (RCT) with vitamin D supplementation have not been conclusive. In the present study 206 subjects were randomised to vitamin D (100 000 IU (2500 µg) as a bolus dose followed by 20 000 IU (500 µg) per week) and 202 to placebo. The Beck Depression Inventory-II (BDI-II) was filled ... -
Smoking and other determinants of bone turnover
Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-25)The balance between bone resorption and formation may be assessed by measurement of bone turnover markers (BTMs), like carboxyl-terminal cross-linked telopeptide of type 1 collagen (CTX-1) and procollagen type 1 amino-terminal propeptide (P1NP). Smoking has been shown to influence bone turnover and to reduce bone mass density (BMD), the exact mechanism for this is, however, not settled. In this ... -
Tracking of serum 25-hydroxyvitamin D during 21 years
Kubiak, Julia Magdalena; Kamycheva, Elena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-11)Background/objectives - Our objective was to evaluate the degree of tracking for serum levels of 25-hydroxyvitamin D [25(OH)D] over time, by using data from three previously conducted surveys of the Tromsø study collected in the years 1994/1995 (Tromsø 4), 2007/2008 (Tromsø 6), and 2015/2016 (Tromsø 7).<p> <p>Subjects/methods - Subjects with valid 25(OH)D measurements in all three surveys were ... -
Vitamin D supplementation does not improve CVD risk factors in vitamin D-insufficient subjects
Kubiak, Julia Magdalena; Thorsby, Per Medbøe; Kamycheva, Elena; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06)<p><i>Objective</i>: Low serum 25(OH)D levels are associated with cardiovascular disease (CVD) and some of its risk factors. However, in interventional studies, the effects of vitamin D supplementation have been uncertain, possibly due to inclusion of vitamin D-sufficient subjects. Our aim was therefore to examine effects of vitamin D supplementation on CVD risk factors in vitamin D-insufficient ...